Science you can build on
Every Regenesis product is backed by independent peer-reviewed research, multi-centre clinical studies, and physician-developed protocols — published in leading international journals.
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Therapeutic Performance of Needle Injection Versus Needle-Free Jet Injector System for Polynucleotide Filler in Skin Rejuvenation
Split-face RCT across 10 patients. CureJet outperformed conventional needle injection on Global Aesthetic Improvement Scale, patient satisfaction, and VAS pain scores — with more pronounced pore and wrinkle improvement.
Journal of Cosmetic Dermatology
Hong JY, Lee YH, Kim HJ, Park KY
Needle-Free Subcision and Hyaluronic Acid Injection Using CureJet for Horizontal Neck Fold Reduction
20-patient study. CureJet subcision increased dermal thickness from 1.02 to 1.58 mm and subcutaneous fat from 0.67 to 2.05 mm. Skin roughness reduced from 3.43 to 1.79 — validated by ultrasound and 3D imaging.
Plastic and Reconstructive Surgery — Global Open
Kim JS, MD
The Effective Delivery of Poly(D,L-lactic Acid) (Juvelook) via Needle-Free Injection (CUREJET) for Facial Rejuvenation
40-patient, 5-session study. GAIS improved from 1.48 to 2.16 at 24 weeks. Patient satisfaction increased from 3.38 to 8.71/10. 3D imaging confirmed sustained lifting and textural improvement.
Aesthetic Plastic Surgery
Seo SB, Wan J, Yoon SE, et al.
Needle-Free Jet Injection of Poly-(Lactic Acid) for Atrophic Acne Scars: Literature Review and Report of Clinical Cases
Systematic review and multi-clinic cases demonstrating effective PLLA delivery via needle-free injector for atrophic acne scars. Histological evidence confirms even intradermal particle distribution.
Journal of Clinical Medicine
Rho NK, Kim HJ, Kim HS, Lee W
Targeted Acne Therapy Using Light-Absorbing Gold Microparticles Combined With Long-Pulsed 1064 nm Nd:YAG Laser
4-patient case series. Standard-dose gold microparticles with Nd:YAG laser produced marked reduction in inflammatory acne lesions, post-acne erythema, and skin oiliness across 3 sessions at 2-week intervals.
Cureus
Pamela R, Sutanto M, Christanty A, et al.
Jet Injectors: Perspectives for Small Volume Delivery with Lasers
Comprehensive review of laser-actuated needle-free jet injectors. Covers precision volume control (pL–mL), skin penetration depth, and combination with laser energy for superficial dermal delivery.
Advanced Drug Delivery Reviews
Schoppink J, Fernandez Rivas D
A Liquid Breakdown Driven Non-Invasive Microjet Injection System
Development and validation of a microjet system achieving 200–330 m/s jet speed and ∼16 Hz frequency with 0.1–1.7 μL per pulse. Both dielectric and laser-induced breakdown sources evaluated in ex-vivo and in-vivo mouse models.
Medical Engineering and Physics
Ham H, Yoh JJ
Synchronization of Skin Ablation and Microjet Injection for Effective Transdermal Drug Delivery
Er:YAG laser-driven combined skin ablation + microjet injection system. Porcine skin studies confirm enhanced transdermal delivery efficiency with compact integrated L-shaped injector design.
Applied Physics A
Jang HJ, Yeo S, Yoh JJ
Assessing the Efficacy of Jet Dispenser Versus Direct Syringe Injection in Controlled Canal Models
Controlled model study demonstrating jet dispenser achieves 100% fill ratio in both straight and curved canal geometries vs direct syringe injection, with zero voids. Validates superior precision and uniformity of jet delivery mechanism.
Scientific Reports (Nature Portfolio)
Song Y, Ham H, Lee WC, Kim RJY
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